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Old 01-16-2008, 10:29 PM   #1
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who wants to live to be 800 ?

source: http://io9.com/345728/geneticists-di...s-to-800-years

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There is now a way to extend the lifespan of organisms so that humans could conceivably live to be 800 years old. In an amazing development, scientists at the University of Southern California have announced that they've extended the lifespan of yeast bacteria tenfold -- and the recipe they used to do it might easily translate into humans. It involves tinkering with two genes, and cutting down your calorie intake. Tests have already started on people in Ecuador.

According to an announcement from PLoS Genetics:

Researchers have created baker's yeast capable of living to 800 in yeast years without apparent side effects. The basic but important discovery, achieved through a combination of dietary and genetic changes, brings scientists closer to controlling the survival and health of the unit of all living systems: the cell. "We're setting the foundation for reprogramming healthy life," says study leader Valter Longo of the University of Southern California.

Longo's group put baker's yeast on a calorie-restricted diet and knocked out two genes - RAS2 and SCH9 - that promote aging in yeast and cancer in humans.

"We got a 10-fold life span extension that is, I think, the longest one that has ever been achieved in any organism," Longo says. Normal yeast organisms live about a week.

"I would say 10-fold is pretty significant," says Anna McCormick, chief of the genetics and cell biology branch at the National Institute on Aging (NIA) and Longo's program officer. The NIA funds such research in the hope of extending healthy life span in humans through the development of drugs that mimic the life-prolonging techniques used by Longo and others, McCormick adds.

Baker's yeast is one of the most studied and best understood organisms at the molecular and genetic level. Remarkably, in light of its simplicity, yeast has led to the discovery of some of the most important genes and pathways regulating aging and disease in mice and other mammals.

Longo's group next plans to further investigate life span extension in mice. The group is already studying a human population in Ecuador with mutations analogous to those described in yeast.

"People with two copies of the mutations have very small stature and other defects," Longo says. "We are now identifying the relatives with only one copy of the mutation, who are apparently normal. We hope that they will show a reduced incidence of diseases and an extended life span."

Longo cautions that, as in the Ecuador case, longevity mutations tend to come with severe growth deficits and other health problems. Finding drugs to extend the human life span without side effects will not be easy.

I've always been a skeptic when it comes to life-extending research, but this has me rethinking my position.
would you even want to live this long ?
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Old 01-16-2008, 10:30 PM   #2
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So is refusing to give it up.

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Old 01-16-2008, 10:35 PM   #3
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screw that, then the population would REALLY be out of control.
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Old 01-16-2008, 11:17 PM   #4
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death penality would be for every crime..(i.e. lying, looking at a girl lustfully, cutting in line...etc.)
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Old 01-16-2008, 11:19 PM   #5
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death penality would be for every crime..(i.e. lying, looking at a girl lustfully, cutting in line...etc.)

no !
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Old 01-16-2008, 11:36 PM   #6
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no !
COULD YOU IMAGINE CLOCKING IN 1 MINUTE LATE FOR WORK AND THE TIME CLOCK WOULD BE ALL LIKE...
A0069b 3 towerexplo1 explosion below
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Old 01-16-2008, 11:41 PM   #7
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mack this isnt the 9/11 thread lol
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Old 01-16-2008, 11:43 PM   #8
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mack this isnt the 9/11 thread lol
only bulding i could find... I guess my joke BOMBED...
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Old 01-16-2008, 11:49 PM   #9
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hahaha
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Old 01-17-2008, 12:02 AM   #10
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haha
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Old 01-17-2008, 12:37 AM   #11
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we are turning into elves!!!! lol.

sign me up. minus the pointy ears i think it would be pretty cool. i feel that a 80 or so year lifespan doesnt allow us alot of time to learn things about life, and more importantly, doesnt allow us enough time to pass those lessons on.

age and wisdom arent the same thing, but they do tend to go together. i think eventually people would just get bored of acting stupid, being hurtful and dumb.
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Old 01-17-2008, 07:24 AM   #12
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I don't think I would like to live 800 years, but 100-120 would be nice. Of course, hopefully the aging effect on the body slows also. Look 40 when you are 60? I agree with Chris that we don't seem to learn all our lessons till 50-60s. OF course that would give the government a reason to push back retirement ages. lol. I still feel the length of our lives shouldn't be put in our own hands though. Neat article.
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Old 01-17-2008, 08:00 AM   #13
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i wouldnt mind..........but if i was all shriveled up .......i wouldnt want to......but if i was still healthy and agile.......bring it on.............lol
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Old 01-17-2008, 10:41 AM   #14
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If healthy.

F*ckin yeah!!!!
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Old 01-17-2008, 10:43 AM   #15
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iwoul love it, the world needs me haha
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Old 01-17-2008, 10:47 AM   #16
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Right now just hitting 80.. looks good...
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Old 01-17-2008, 10:54 AM   #17
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I would say no, because you would watch everyone you love die one at a time until you had no more family, no more friends, which i guess you could always replenish your friends but i wouldn't want to.
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Old 01-17-2008, 11:40 AM   #18
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Quote:
Originally Posted by mekrew View Post
source: http://io9.com/345728/geneticists-di...s-to-800-years



would you even want to live this long ?
talk about over population!
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We must use terror, assassination, intimidation, land confiscation, and the cutting of all social services to rid Galilee of its Arab population.
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